TITLE:
Inflammatory Bowel Diseases: What Do We Still Need to Investigate?
AUTHORS:
Marina Taus, Debora Busni, Daniele Fumelli, Arianna Paci, Giulia Nicolai, Albano Nicolai
KEYWORDS:
Inflammatory Bowel Desease, Fecal Mass Transplantation, Nutrition and Macrobiota
JOURNAL NAME:
Open Journal of Gastroenterology,
Vol.5 No.10,
October
28,
2015
ABSTRACT: Inflammatory bowel disease (IBD) including Crohn (CD) and ulcerative colitis (UC), is intestinal disorders with an unknown specific etiology. Many factors are involved in the pathogenesis: genetic, environment, nutrition, immunity and intestinal dysbiosis. In the present work, we review the most important trigger mechanisms involved in IBD, with a particular regard to the role of microbiota and fecal mass transplantation as a new therapeutic approach, that even if it can be considered safe and effective, data are necessary regarding all procedures not yet standardized and timing of treatment.