TITLE:
Migraine History and Breast Cancer Risk: A Systematic Review and Meta-Analysis
AUTHORS:
Shahab Rezaeian, Yousef Veisani, Mohammad Ghorbani, Ali Delpisheh, Hedayat Abbastabar
KEYWORDS:
Migraine, Breast cancer, Meta-Analysis
JOURNAL NAME:
Advances in Breast Cancer Research,
Vol.4 No.3,
July
3,
2015
ABSTRACT: Objective: The relationship between migraine and breast cancer risk has
been reported inconsistently across different epidemiological studies. This
meta-analysis was performed to explore the overall effect of migraine on breast
cancer risk. Method: An electronic search of different major databases was
conducted, including PubMed, Scopus, ScienceDirect, and the Cochrane library
until February 1st, 2015. Of 652 retrieved studies, six
population-based studies including two cohort studies with 130,812 and four
case-control studies with 14,396 people were included in the analysis. Results:
There was an inverse relationship between migraine and breast cancer risk (OR =
0.77; 95% CI: 0.64, 0.92). Conclusion: The results of this meta-analysis showed
that women with migraine history have a decreased risk of breast cancer.
Further biological studies are needed to address the association.