TITLE:
Neocollagenesis in Non-Invasive Aesthetic Treatments
AUTHORS:
Ilja L. Kruglikov
KEYWORDS:
Neocollagenesis; Aesthetic Treatments; Procollagen; Mature Collagen; Turnover
JOURNAL NAME:
Journal of Cosmetics, Dermatological Sciences and Applications,
Vol.3 No.1A,
January
9,
2013
ABSTRACT: Dermal neocollagenesis is often assumed to be the main reason of visible skin improvement after different non-invasive and minimal invasive aesthetic treatments. However, the very slow dynamics of the mature collagen remodelling in the extra cellular matrix (ECM) of dermis, with a half-life time of 15 years, renders every observable upregulation of collagen production insufficient to replace a significant part of the matrix during the short time in which it is claimed skin improvement takes place.