TITLE:
Epidemiological and Clinical Profile of Breast Cancer at Bamako Radiotherapy Center
AUTHORS:
A. S. Kone, A. Diakite, I. M. Diarra, K. Diabate, M. A. Camara, Y. L. Diallo, S. Sidibe
KEYWORDS:
Breast Cancer, Epidemiology, Clinic
JOURNAL NAME:
Journal of Cancer Therapy,
Vol.10 No.9,
September
11,
2019
ABSTRACT: Breast cancer is a major public health problem because of its incidence
and mortality. Purpose: To establish the epidemiological and clinical
characteristics of breast cancer seen at the radiotherapy center at the Mali
Hospital of Bamako. Patients and methods: It was a retrospective, descriptive
study of data from patients seen for breast cancer at the Center of
Radiotherapy of Mali Hospital between April 2014 and December 2016. The
parameters studied were: age, sex, family history of breast cancer, menopausal
status, parity, breast tumor location, histological type, histological grade,
cancer classification stage. Results: 134 cases of breast cancer were collected,
with a frequency of 15%. The sex ratio (H/F) of 0.007. The patient’s mean age
was 47 ± 11 years old. The most represented age groups were 33 - 47 years old
with 45.5% and 48 - 62 years old with 39%. Three percent (3%) of patients had a
family history of breast cancer. Fifty (50%) of the patients were menopausal.
The main clinical signs found were : mammary nodules (98%), mastodynia (65%), nodes (67%). Invasive ductal
carcinomas were found in 94% of patients, followed by infiltrating lobular
carcinomas with 3.7% and metaplastic carcinomas with 1.7%. SBR Grades II and III were mostly found with 37% and 23%. The average tumor size was 87 mm ±
43. Stage III was predominantly represented with 72%, followed by Stage II with
24% and Stages I and IV with 2% each. Conclusion: Breast cancer is common and reaches both before and after 50 years;
the diagnosis is usually late; hence it is the importance of raising awareness and screening before the age of 50 and popularizing some complementary tests to better understand
the prognosis of this disease and promote more targeted and conservative
treatments that will improve survival.