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has been cited by the following article:

• TITLE: Study on the Relationship between Stromal Cell-Derived Factor-1 (SDF-1) and Gastric Cancer

  AUTHORS: Xiulian Xu, Yurong Song, Shoujiang Wei, Chongshu Wang

  KEYWORDS: SDF-1, Clinicopathological Characteristics, Gastric Cancer, HP

  JOURNAL NAME: Health, Vol.11 No.3, March 14, 2019

  ABSTRACT: Whether SDF-1 is related to the occurrence and development of gastric cancer, we collected gastric cancer tissues and corresponding non-cancerous gastric tissues from 52 patients with gastric cancer, and detected the expression of SDF-1 by real-time fluorescence quantitative polymerase chain reaction (RT-PCR) and immunohistochemistry. We also analyzed the relationship between the expression level and clinicopathological characteristics. In both cases SDF-1 gene and protein expression in gastric cancer tissues were significantly higher than in corresponding non-cancerous gastric tissues (both P 0.05, respectively). Also, there were no significant relations hip in gastric cancer tissues of Helicobacter pylori (HP)-positive patients and negative ones (P > 0.05). The result of the study showed that SDF-1 might play a significant role in the process of formation and development of gastric cancer as an oncogene, but could not be used as an index to judge prognosis and predict recurrence.