TITLE:
Effective Treatment of Vulvar-Vaginal Complaints in Women Taking Combined Oral Contraceptive with a New Medical Device in Gel: A Pilot Study
AUTHORS:
Filippo Murina, Franco Vicariotto
KEYWORDS:
Vaginal Dryness, Dyspareunia, Oral Contraceptive, Red Clover
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.9 No.3,
March
6,
2019
ABSTRACT: Objective: To assess efficacy and tolerability of a new medical device in gel based
on the synergic combination of NioskinTM Red Clover Extract noisome (NRC) and SylTechTM system (SB), a complex of silicium microcrystals covalently bound with
silver ions associated with hyaluronic acid to the treatment of vulvo-vaginal
dryness and dyspareunia in women taking combined oral contraceptive (COC). Methods: Forty eight women were treated for 12 weeks with NRC + SB vaginal gel (0.75
g/day) for 3 weeks. After therapy, symptoms (dyspareunia and dryness) were
evaluated through a 10-cm VAS. Visual examination of the vagina and vulvar
vestibule was also conducted, which included observations for petechiae,
pallor, friability, dryness, and redness in the mucosa. Ratings were based on a
4-point scale (0, none; 1, mild; 2, moderate; 3, severe). Results: NRC +
SB vaginal gel appears to be effective for relief vulvo-vagianl dryness and
dyspareunia and an improvement of vaginal and vestibular trophism was noted. Conclusion: NRC + SB vaginal gel proved good treatment options for relief of vulvovaginal
symptoms in women who take COC.