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https://doi.org/10.1002/art.1780330203

has been cited by the following article:

• TITLE: Association of COL1A1 rs180012 SNP and Fibromyalgia Suggests the Implication of Collagen Structure in Musculoskeletal Pain

  AUTHORS: Isabel Navarro-Vera, José Antonio Casajús, Manuel J. López-Pérez, Carmen Díez-Sánchez

  KEYWORDS: Fibromyalgia, Genotype, Collagen, Bone Mineral Density, SP1

  JOURNAL NAME: Advances in Bioscience and Biotechnology, Vol.9 No.2, February 23, 2018

  ABSTRACT: Fibromyalgia (FM) is a complex, chronic condition, which causes widespread musculoskeletal pain, fatigue and a variety of other symptoms. Many polymorphisms related to neuroendocrine system function as the ApoE isoforms, Val158Met polymorphism in COMT, as well as a 44 bp deletion located in 5-HTTLPR, have been studied. Other polymorphisms have been related to inflammatory response such as the 70 bp VNTR in IL-4 or to citokine levels. Furthermore, some studies focused on finding out new FM related SNPs, have been performed by genome wide association scan (GWAS). The target of this work was to study a possible linkage of a collagen type I polymorphism (COL1A1 rs180012 SNP) affecting bone mineralization, with fibromyalgia. Results obtained show a clear association of ss homozygous genotype with FM patients no dependent on bone mineralization.