标题:
Recurrent Pregnancy Loss in Patients with Polycystic Ovary Syndrome: A Case Control Study
作者:
Lulwa Ashaq, Yousef Al Mazer, Nourah Al Qahtani
关键词:
Polycystic Ovary, Recurrent Abortion
期刊名称:
Open Journal of Obstetrics and Gynecology,
Vol.7 No.11,
October
18,
2017
摘要: Objectives: To identify different biophysical and hormonal factors that could
contribute to recurrent pregnancy loss in Saudi women who have been diagnosed
with polycystic ovary syndrome. Study Design: Case-control study. Settings: Infertility clinic in Dammam Maternity and Children Hospital. Cases: PCOS patients with recurrent pregnancy loss. Controls: PCOS
patients without recurrent pregnancy loss. Results: The prevalence of
recurrent abortion in PCOS patients was 31%. There was no significant
difference between the cases and the controls in the age, 33.1 years versus
31.9 years, BMI, 31.4 kg/m2 versus 31.6 kg/m2 respectively. There was no significant difference in the successful pregnancies
outcome in cases and controls, term deliveries 84% versus 90%, preterm
deliveries 10% versus 5%, twin pregnancy 6% versus 5% respectively. There was
no significant difference in the hormonal profile (prolactin, LH, FSH, LH/FSH
ratio, TSH, progesterone, testosterone) between cases and controls. Serum
estradiol level was significantly lower in the cases compared to the controls,
55.5 pg/mL versus 83.9 pg/mL respectively (p Conclusion: PCOS patients with recurrent abortions had no significant increase in the age,
BMI, preterm pregnancy, multiple gestation and ectopic pregnancy. The hormonal
profile (prolactin, LH, FSH, LH/FSH ratio, TSH, progesterone, testosterone) was
comparable between the cases and the controls, except for serum estradiol
level, which was significantly lower in PCOS patients with recurrent abortions.