TITLE:
Predictive Study of Velocimetry in the Coronary Artery after Iodinated Contrast Agent Injection
AUTHORS:
Nora Hocine, Julie Colnot, Hélène Masset, Didier Franck
KEYWORDS:
Coronary Artery, Iodinated Contrast Agent, Blood Flow
JOURNAL NAME:
International Journal of Medical Physics, Clinical Engineering and Radiation Oncology,
Vol.6 No.1,
February
28,
2017
ABSTRACT: This study
aims to determine the retention time of iodinated contrast agents (ICA) in the coronary
artery. The mechanical aspect of ICA displacement was studied in order to better
understand the effect of these products on the inner wall of the artery of patients
with coronary artery stenosis, undergoing repeated imaging examinations with iodinated
contrast agents. ICA flow, ICA and blood flow in the artery were modelled. The fluid
was regarded to be viscous, incompressible and Newtonian. Blood flow was presumed
to be unidirectional, laminar and unstationary. Iodine flow velocity and retention
time were calculated using the Runge-Kutta 4th order method programmed in C++ and
MatLab R2013a language. The results showed that for coronary artery CT-scans, ICA
retention time is 1 minute 40 seconds and for coronary arteriography it is between
2.41 and 3.61 seconds. The values calculated were compared to theoretical values
and to clinical observations. The results enabled us to validate our model.