TITLE:
UV Visible Spectrophotometric Determination of the Quality of Antiretroviral Drugs Distributed in Kinshasa
AUTHORS:
Erick Ntambwe Kamangu, Jérémie K. Mbinze, Arnold M. Mingu, Jacquie B. Bolavie, Georges Lelo Mvumbi, Richard Lunganza Kalala, Gauthier Kahunu Mesia, Mariano Lusakibanza, Jean Mavar, Roland D. Marini
KEYWORDS:
Spectrophotometry, UV-Visible, ARV, Kinshasa
JOURNAL NAME:
Open Access Library Journal,
Vol.4 No.2,
February
15,
2017
ABSTRACT: Background:
Antiretrovirals (ARVs) are the molecules used in the fight against infection by
the Human Immunodeficiency Virus (HIV). Their main objective is to stop the
virus from replicating and thus allow the immune system to recover. In 2001,
the program to fight against HIV/AIDS United Nations (UNAIDS) and its partners
has decided to strengthen the pharmaceutical channel and improve access to good
quality care. Thus ARV quality control is recommended. Objective: The objective
of this work was to monitor the quality of ARVs distributed in Kinshasa. Methodology:
In this work, UV-visible spectrophotometry is used for the analysis of ARVs
presented in simple form distributed in the city of Kinshasa. Results: The
results of this work show that the stated and analyzed ARVs contain active
ingredients; there is no placebo. Ten percent of these ARVs are non-compliant
with regard to dosing of the active test. Conclusion: These results confirm the
need to control these drugs to protect patients from adverse consequences
related to their poor quality.