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has been cited by the following article:

• TITLE: Inverse relationship between glomerular hyperfiltration and C-peptide level in Type 1 diabetes

  AUTHORS: Anissa Messaaoui, Sylvie Tenoutasse, Christian Mélot, Harry Dorchy

  KEYWORDS: Type 1 Diabetes, Hyperfiltration, Nephropathy, C-Peptide, Glycated Hemoglobin

  JOURNAL NAME: Journal of Diabetes Mellitus, Vol.4 No.1, February 14, 2014

  ABSTRACT: Background: Increased glomerular filtration rate (GFR) commonly develops in early diabetes and is closely correlated with the development of diabetic nephropathy. Objective: The aim was to study the relationship between GFR, C-peptide level and other parameters at diagnosis of Type 1 diabetes. Methods: We determined GFR, Cpeptide level, glycated hemoglobin (HbA1c), body mass index (BMI) SDS and loss of weight at diagnosis of Type 1 diabetes in 495 children (231 females). Linear and multiple regression analysis was used to test for the associations between GFR and other parameters. Results: In the 495 patients, GFR median (interquartile range) was increased vs normal values (p = 0.0001). GFR was significantly negatively correlated with age (p