Synthesis and Antimicrobial Activity of a New Class of Sulfone Linked Bisheterocycles


A new and novel class of bis(heterocycles) viz., bis pyrroles, pyrrolyl pyrazoles and pyrrolyl isoxazoles are prepared from 1-aroyl-2-styrylsulfonylethenes by 1,3-dipolar cycloaddition of tosylmethyl isocyanide, diazomethane, nitrile imines and nitrile oxides. The lead compounds are screened for antimicrobial activity.

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V. Padmavathi, T. Lakshmi, B. Venkatesh and K. Mahesh, "Synthesis and Antimicrobial Activity of a New Class of Sulfone Linked Bisheterocycles," International Journal of Organic Chemistry, Vol. 1 No. 3, 2011, pp. 78-86. doi: 10.4236/ijoc.2011.13013.

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The authors declare no conflicts of interest.


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