In Vitro Preliminary Evidences on the Antioxidant Properties of Biogenic Amines

Roberto Stevanato, Mariangela Bertelle, Sabrina Fabris

Department of Molecular Sciences and Nanosystems, University Ca’ Foscari of Venice, Venice, Italy.
Department of Molecular Sciences and Nanosystems, University Ca’ Foscari of Venice, Venice, Italy..

DOI: 10.4236/pp.2013.49097                

Abstract

Antioxidant properties of the principal biogenic amines were determined in vitro by four analytical methods—Folin Ciocalteu, DPPH, enzymatic and inhibition of lipid peroxidation—in order to avoid possible measuring-method linked mistakes. Different results are obtained, depending on the parameters that each of them measures. The combination of the data indicates that all examined amines show antioxidant characteristics: in particular, tyramine, serotonin, L-norepinephrine, (-)-epinephrine and dopamine owing to their (poly)phenolic structure too, while aliphatic polyamines-spermine, spermidine, putrescine and cadaverine-histamine, melatonin and tryptamine appear to act specifically on the oxygen-consuming species involved in the lipid peroxidation of polyunsaturated fatty acids.

Keywords

Biogenic Amines; Antioxidants; Lipid Peroxidation; DNA Protection; Membrane Protection

Conflicts of Interest

The authors declare no conflicts of interest.

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