IgG4-Related Disease Presenting as a Soft Tissue Tumor Affecting Skeletal Muscle: A Case Report ()
David Sáez Martínez,
Felipe López Oliva,
María Jesús Fernández Aceñero,
Elena Fontoira Moyer,
Juan Luis Arranz Cozar
Oncology Department, Fundación Jiménez Díaz, Mad- rid, Spain.
Ortrhopedic Surgery Department, Fundación Jiménez Díaz, Madrid, Spain.
Pathology Department, Fundación Jiménez Díaz, Mad- rid, Spain.
Radiology Department, Fundación Jiménez Díaz, Madrid, Spain.
DOI: 10.4236/ijcm.2013.412A1001
PDF
HTML
4,325
Downloads
5,854
Views
Citations
Abstract
Background: IgG4-related disease is a systemic lymphoproliferative syndrome that shows
IgG4-producing plasma cell expansion in affected organs with fibrotic or
sclerotic changes. The lacrimal glands, salivary glands and pancreas are
typically affected. We report a case of IgG4-related disease presenting a soft
tissue tumor affecting skeletal muscle. Case Report: A 32-year-old man presented a soft tissue mass
in his left arm. Magnetic resonance imaging revealed a spindle like, peripheral
mass, in the lateral head of the triceps of his left arm. Tru-Cut Biopsy
provided the diagnosis of IgG4-related disease affecting skeletal muscle.
Glucocorticoid treatment was effective. Conclusion: To our knowledge, this is the first reported case of IgG4-related disease
affecting skeletal muscle and presenting a soft tissue mass.
Share and Cite:
D. Martínez, F. Oliva, M. Fernández Aceñero, E. Moyer and J. Arranz Cozar, "IgG4-Related Disease Presenting as a Soft Tissue Tumor Affecting Skeletal Muscle: A Case Report,"
International Journal of Clinical Medicine, Vol. 4 No. 12A, 2013, pp. 1-4. doi:
10.4236/ijcm.2013.412A1001.
Conflicts of Interest
The authors declare no conflicts of interest.
References
|
[1]
|
T. A. Damron, “Oncology and Basic Science,” Lippincott Williams & Wilkins, Philadelphia, 2008.
|
|
[2]
|
J. H. Stone, Y. Zen and V. Deshpande, “Mechanisms of disease: IgG4-related disease,” The New England Journal of Medicine, Vol. 366, No. 6, 2012, pp. 539-551.
http://dx.doi.org/10.1056/NEJMra1104650
|
|
[3]
|
H. Umehara, K. Okazaki, Y. Masaki, et al., “Comprehensive Diagnostic Criteria for IgG4-Related Disease (IgG4RD), 2011,” Modern Rheumatology, Vol. 22, No. 1, 2012, pp. 21-30. http://dx.doi.org/10.1007/s10165-011-0571-z
|
|
[4]
|
M. Yasufumi, K. Nozomu and U. Hisanori, “IgG4-Related Disease: A Novel Lymphoproliferative Disorder Discovered and Established in Japan in the 21st Century,” Journal of Clinical and Experimental Hematopathology, Vol. 51, No. 1, 2011, pp. 13-20.
http://dx.doi.org/10.3960/jslrt.51.13
|
|
[5]
|
H. M. Moutsopoulos, G. E. Fragoulis and J. H. Stone, “Overview of IgG4-Related Disease,” 2013.
http://www.uptodate.com/contents/overview-of-igg4-related-disease
|
|
[6]
|
M. N. Carruthers, J. H. Stone and A. Khosroshahi, “The Latest on IgG4-RD: A Rapidly Emerging Disease,” Current Opinion in Rheumatology, Vol. 24, No. 1, 2012, pp. 60-69. http://dx.doi.org/10.1097/BOR.0b013e32834ddb4a
|