Determination of Triclocarban, Triclosan and Methyl-Triclosan in Environmental Water by Silicon Dioxide/Polystyrene Composite Microspheres Solid-Phase Extraction Combined with HPLC-ESI-MS

Yinan Wang, Pengfei Li, Yan Liu, Bing Chen, Jinyu Li, Xikui Wang

School of Chemical Engineering, Shandong Polytechnic University, Jinan, China.
School of Chemical Engineering, Shandong Polytechnic University, Jinan, China; Jinan Water Group Company Limited, Jinan, China.
School of Chemical Engineering, Shandong Polytechnic University, Jinan, China; School of Biological Science and Technology, Beijing Forestry University, Beijing, China.

DOI: 10.4236/gep.2013.12003                

Abstract

This paper developed a sensitive and efficient analytical method for triclocarban (TCC), triclosan (TCS) and Methyl-triclosan (MTCS) determination in environmental water, which involves enrichment by using silicon dioxide/polystyrene composite microspheres solid-phase extraction and detection with HPLC-ESI-MS. The influence of several operational parameters, including the eluant and its volume, the flow rate and acidity of water sample were investigated and optimized. Under the optimum conditions, the limits of detection were 1.0 ng/L, 2.5 and 4.5 ng/L for TCC, TCS, and MTCS, respectively. The linearity of the method was observed in the range of 5-2000 ng/L, with correlation coefficients (r²) >.99. The spiked recoveries of TCC, TCS and MTCS in water sampleswereachieved in the range of 89.5% -96.8% with RSD below 5.7%. The proposed method has been successfully applied to analyze real water samples and satisfactory results were achieved.

Keywords

Triclocarban; Triclosan; Solid-Phase Extraction; Silicon Dioxide/Polystyrene Composite Microspheres; HPLC-ESI-MS/MS

Conflicts of Interest

The authors declare no conflicts of interest.

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