Stabilization of Circadian Rhythm, Its Augmentation by Bright Light Treatment and Its Importance for ADHD and Depression of Adolescents

Helmut Niederhofer

Department of Child and Adolescent Psychiatry and Psychotherapy, Saechsisches Krankenhaus für Psychiatrie und Neurologie Rodewisch Bahnhofstrasse, Rodewisch, Germany..

DOI: 10.4236/nm.2013.43024                

Abstract

Objective: ADHD is characterized by the progressive development of, impulsiveness, attentional difficulties and sometimes also excessive hyperactivity. Main biological reason is a quantitative reduction of the neurotransmitter dopamine in the forebrain. A lack of dopamine is also typical for depressive disorders. Methods: Bright light therapy is proven to be effective in treating depression. Purpose of our study is to verify the therapeutic effectiveness of Bright light therapy in subjects affected by ADHD. Results: Results show a significant improvement which lasts for at least 4 weeks, which is superposed by regulation of the circadian rhythm. Initial decrease of especially morning saliva melatonin levels, due to regular sleep under in-patient conditions, is followed by symptom improvement and a raising evening melatonin level, due to activation during the day. This level decreases as soon as activation is ceased. Conclusion: Bright light therapy seems to be effective as add-on therapy for ADHD, but in fact, stabilization of the circadian rhythm is the most important therapeutic intervention, either for ADHD or for depression, as demonstrated in another study.

Keywords

ADHD; Circadian Rhythm; Bright Light Therapy

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1]	G. H. Moll, H. Heinrich, G. Trott, S. Wirth and A. Rothenberger, “Deficit Intracortical Inhibition in Drug-Naive Children with Attention Deficit Hyperactivity Disorder Is Enhanced by Methylphenidate,” Neuroscience Letters, Vol. 21, 2000, pp. 121-125. doi:10.1016/S0304-3940(00)00980-0
[2]	J. Hoeppner, F. Padberg, G. Domes, A. Zinke, S. C. Herpertz, N. Grossheinrich and U. Herwig, “Influence of Repetitive Transcranial Magnetic Stimulation on Psychomotor Symptoms in Major Depression,” European Archives of Psychiatry and Clinical Neuroscience, Vol. 260, No. 3, 2010, pp. 197-202. doi:10.1007/s00406-009-0039-8
[3]	H. Niederhofer, “Effectiveness of the Repetitive Transcranical Magnetic Stimulation (rTMS) of 1 Hz for Attention-Deficit Hyperactivity Disorder (ADHD),” Psychiatria Danubia, Vol. 20, No. 1, 2008, pp. 91-92.
[4]	C. Even, C. M. Schroeder, S. Friedman and F. Rouillon, “Efficacy of Light Therapy in Nonseasonal Depression: A Systematic Review,” Journal of Affective Disorders, Vol. 108, No. 1, 2008, pp. 11-23. doi:10.1016/j.jad.2007.09.008
[5]	Y. E. Rybak, H. E. McNeely, B. E. Mackenzie, U. R. Jain and R. D. Levitan, “An Open Trial of Light Therapy in Adult Attention-Deficit/Hyperactivity Disorder,” Journal of Clinical Psychiatry, Vol. 67, 2006, pp. 1527-1535. doi:10.4088/JCP.v67n1006
[6]	C. H. Goyette, C. K. Conners and R. F. Ulrich, “Normative Data on Revised Conners Parent and Teacher Rating Scales,” Journal of Abnormal Child Psychology, Vol. 6, No. 2, 1978, pp. 221-236. doi:10.1007/BF00919127
[7]	C. I. Eastman, “What the Placebo Literature Can Tell Us about Light Therapy for SAD,” Psychopharmacol Bulletin, Vol. 26, No. 4, 1990, pp. 495-504.
[8]	H. Niederhofer and K. Klitzing, “Bright Light Treatment as Add-On Therapy for Depression in 28 Adolescents: A Randomized Trial,” Primary Care Companion CNS Disorders, Vol. 13, No. 6, 2011.