Green Synthesis of Silver Nanoparticles with High Fungicidal Activity from Olive Seed Extract

Habeeb Khadri, Mohammad Alzohairy, Avilala Janardhan, Arthala Praveen Kumar, Golla Narasimha

Applied Microbiology Laboratories, Department of Virology, Sri Venkateswara University, Tirupati, India.
Department of Medical Laboratory, College of Applied Medical Sciences, Qassim University, Qassim, Kingdom of Saudi Arabia.

DOI: 10.4236/anp.2013.23034                

Abstract

Silver nanoparticles in the form of silver based chemicals trace back their origin to time immemorial since the dilute forms of silver nitrate were used in place of antibiotics before they dominated the field of medicine. But, it has now become necessary to explore the anti-microbial properties of silver based chemicals again due to the microbes gaining resistance against the wide range of present day antibiotics. The advancements in the field of medicine and technology started to coalesce to combat the adaptability of microbes as they successfully become tolerant to antibiotics and it manifested in the form a current technology, Nanomedicine. Nanomedicine deals about the medicines at a nano scale to rarefy the intensity of medicine to unaffected tissues and reduce the volume of medicine used. In the present context, our attempt is to develop potential anti-microbial particles in the form of silver nanoparticles by using the biological phenomena which we call Green synthesis an eco-friendly approach to conventional chemical synthesis. The enzymatic machinery of the olive seeds has been exploited to produce silver nanoparticles and test their efficacy as antifungal agents before we characterized their physical properties using UV-Vis, TEM, and FTIR analysis. The efficacy of these particles as antagonists on fungal pathogen Aspergillus niger a causative agent of Aspergillosis in human beings and is promising and they have a lot of scope for the purpose and hope the technology leads the next generation of anti-microbials.

Keywords

Olive Seeds; Silver Nanoparticles; Characterization; Fungicidal Activity

Conflicts of Interest

The authors declare no conflicts of interest.

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