Brain Interactions between Extinction and Reconsolidation in the Treatment of Fear Memories

DOI: 10.4236/nm.2011.23032   PDF   HTML   XML   4,286 Downloads   8,306 Views   Citations


Memory traces become labile at the time of retrieval, and this initiates two protein synthesis-dependent processes in the brain: extinction, which inhibits their further retrieval, and reconsolidation, which may enhance retrieval or change the memory’s content. Extinction may itself suffer reconsolidation. Interactions between these processes may be applied to the treatment of fear memories, such as those underlying the post-traumatic stress disorder.

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D. Sartor, N. Fiorenza, J. Myskiw and I. Izquierdo, "Brain Interactions between Extinction and Reconsolidation in the Treatment of Fear Memories," Neuroscience and Medicine, Vol. 2 No. 3, 2011, pp. 232-238. doi: 10.4236/nm.2011.23032.

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The authors declare no conflicts of interest.


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