Journal of Biomedical Science and Engine... > Vol.8 No.9, September 2015

Okwuchukwu Ani¹, Sam Omenyi², Chinonso Achebe^2*

¹Department of Mechanical and Production Engineering, Enugu State University of Science and Technology, Agbani, Nigeria.
²Department of Mechanical Engineering, Nnamdi Azikiwe University, Awka, Nigeria.

In the twenty first century research works, there may be a need to achieve a more reliable research result through a synergy between engineers and biological researchers. The peak absorbance data for various interacting systems were measured. These were used to show that the antiretroviral drug has the effect of increasing the peak absorbance values of both the uninfected and infected blood components, i.e., the drugs are made able to increase the light absorption capacity of the blood cells. For drug 2 that contains three components including Efavirenz, the drug effect on lymphocytes was increased by about 38% for patients that had been on antiretroviral drug treatment. Mathematical models were proposed and used in determining the coating effectiveness of antiretroviral drugs in the presence and absence of HIV. The use of the findings of this work by pharmaceutical industries may help in the search for more effective antiretroviral drugs for the treatment of HIV patients.

Absorbance, Transmittance, Dielectric Constant, Human Immunodeficiency Virus, Antiretroviral Drug, Coating Effectiveness, Lymphocyte, Wavelength

Ani, O. , Omenyi, S. and Achebe, C. (2015) The Effects of Antiretroviral Drugs on the Absorbance Characteristics of HIV-Infected Blood. Journal of Biomedical Science and Engineering, 8, 571-581. doi: 10.4236/jbise.2015.89053.