Quality of Life of the Patients Suffering from Chronic Liver Diseases at the University Health Center Campus of Lome


Objective: Assess the quality of life (QOL) of the patients suffering from chronic liver diseases in our service. Patients and Method: A transversal prospective study conducted at the service of hepatology and gastroenterology at the University health center Campus of Lomé from August 1, 2013 to August 31, 2014. We have used the short form 36 health survey questionnaire (SF-36). Patients of cirrhosis and hepatocellular carcinoma admitted during the said period were selected. Patients suffering from any other chronic diseases such as psychiatric or emotional troubles; linguistic or cognitive deficiencies that could hamper the dependability of the questionnaire were excluded. Results: The average age of the patients was 46 ± 12 years old with a male predominance (sex-ratio: 2.9). Our patients were distributed into 47.4% of cirrhosis and 52.6% of CHC. Those chronic liver diseases etiologies were alcoholic (57%), B viral (66%) and C viral (12.3%). The assessment of QOL showed an overall average score of 76.34 ± 21.1; a mean score of 30.4 ± 86.8 for the physical dimension and 36.5 ± 10.3 for the mental dimension. Patients with viral liver disease had poorer physical summary score (p = 0.000) and poorer mental summary score (p = 0.014) compared to alcoholic patients. Alcohol influenced the physical dimension of the patients (p = 0.000) while the mental dimension was more affected by the age of patients (p = 0.0035). Conclusion: The quality of life is altered by the patients suffering from chronic liver diseases (p = 0035) with regard to our context. This is so in particular with those identified to be viral infected.

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Bagny, A. , Bouglouga, O. , Lawson-Ananissoh, L. , Dusabe, A. , Kaaga, Y. , Balaka, A. , Djibril, M. and Redah, D. (2015) Quality of Life of the Patients Suffering from Chronic Liver Diseases at the University Health Center Campus of Lome. Open Journal of Gastroenterology, 5, 88-93. doi: 10.4236/ojgas.2015.57015.

Conflicts of Interest

The authors declare no conflicts of interest.


[1] Glise, H. and Wiklund, I. (2002) Health-Related Quality of Life and Gastrointestinal Disease. Journal of Gastroenterology and Hepatology, 17, S72-S84.
[2] Bouglouga, O., Bagny, A., Djibril, M.A., Lawson-Ananissoh, L.M., Kaaga, Y.L., Redah, D., et al. (2012) Aspects épidémiologiques, diagnostiques et évolutifs de la cirrhose hépatique dans le service d’hepato-gastroenterologie du chu campus de Lomé. Journal de Recherches Scientifiques de l’Université de Lomé (Togo), Série D, 14, 1-7.
[3] Bouglouga, O., Bagny, A., Lawson-Ananissoh, L.M., Djibril, M.A., Redah, D. and Agbetra, A. (2012) La prise en charge du carcinome hépatocellulaire progresse-t-elle en Afrique noire. Revue Médicale de Madagascar, 2, 176-179.
[4] Simpson, K.J. and Finlayson, N.D. (1995) Clinical Evaluation of Livré Disease. Baillieres Clinical Gastroenterology, 9, 639-659.
[5] Younossi, Z.M. and Guyat, G. (1998) Quality-of-Life Assessments and Chronic Liver Disease. American Journal of Gastroenterology, 93, 1037-1041.
[6] Ware, J.E. and Sherbourne, C.D. (1992) The MOS 36-Item Short-Form Health Survey (SF-36). I. Conceptual Frame-work and Item Selection. Medical Care, 30, 473-483.
[7] Couzigou, P. (2002) Qualité de vie des personnes malades atteintes d’hépatite chronique C: Effet du traitement. Gastroentérologie Clinique et Biologique, 26, 257-263.
[8] Djibril, M.A., Bagny, A., Bouglouga, O., M’ba, K.B., Redah. D. and Agbetra, A. (2011) Pathologies hospitalières du quatrième age dans un service d’hépato-gastroentérologie en milieu africain noir: Cas du CHU Campus de Lomé (Togo). Journal de Recherches Scientifiques de l’Université de Lomé (Togo), Série D, 13, 39-45.
[9] Patinga, C., Lopez, L., Perez, M., Rodriguez, M., Linares, A., Dieguez, L.G., et al. (2005) Quality of Life in Cirrhotic Patients and Liver Transplant Recipients. Psicothema, 17, 143-147.
[10] Popovic, D.J., Kovacevic, N.V., Tepavcevic, G.Z., Alempijevic, T.M., Spuran, M.M., Krstic, M.N., et al. (2013) Validation of the Chronic Liver Disease Questionnaire in Serbian Patients. World Journal of Gastroenterology, 19, 4950-4957.
[11] Desmorat, H., Combis, J.M. and Pradat P. (2005) Assessment of Quality of Life in Chronic Hepatitis C: Effet of Traitement. Gastroentérologie Clinique et Biologique, 27, 1-7.
[12] Younossi, Z.M., Guyatt, G., Kiwi, M., Boparai, N. and King, D. (1999) Develeppement of a Disease Specific Questionnaire to Mensuré Health Related Quality of Life in Patients with Chronic Liver Disease. Gut, 45, 295-300.
[13] Couzigou, P. (2002) Qualité de vie des personnes malades atteintes d’hépatite chronique C: Effet des traitements. Gastroentérologie Clinique et Biologique, 26, 257-263.
[14] Oronsaye, F.E. and Oronsaye, J.I. (2004) Prevalence of HIV-Positives and Hepatitis B Surface Antigen-Positives among Donors in the University of Benin Teaching Hospital, Nigeria. Tropical Doctor, 34, 159-160.
[15] Zuberi, B.F., Memon, A.R., Afsar, S., Qadeer, R. and Kumar, R. (2007) Correlation of Quality of Life in Patients of Cirrhosis of Liver with Etiology and Disease Severity Using Disease-Specific Quality of Life Questionnaire. Journal of Ayub Medical College Abbottabad, 19, 7-11.
[16] Ray, I., Dutta, D., Basu, P. and De, B.K. (2010) Quality of Life Assessment of Patients with Chronic Liver Disease in Eastern India Using a Bengali Translation Chronic Liver Disease Questionnaire. Indian Journal of Gastroenterology, 29, 187-195.
[17] Siebert, U., Ravens-Sieberer, U., Greiner, W., Smezynski, G., Wong, J.B., Kuntz, K.M., et al. (2001) Patients Based Health Related Quality of Life in Different Stages of Chronic Hepatitis C. Hepatology, 34, 222A.
[18] Roudot-Thoraval, F., Abergel, A., Ahart, F., Bourliere, M., Desmorat, H., Fagnani, F., et al. (2001) Hepavir. Premiere étude observationnelle d’une cohorte de malades traités par interferon alpha 2a en monothérapie, évaluation de l’asthé-nie et de ses répercussions sociales. Gastroentérologie Clinique et Biologique, 25, 1061-1066.
[19] Remy, P.J., Daures, J.P., Tanguy, G., Khemissa, F., Chevrier, M., Lezotre, P.L., et al. (1999) Mesure de la qualité de vie chez les malades ayant une hépatite chronique virale C: Validation d’un indicateur général et d’un indicateur spécifique. Gastroentérologie Clinique et Biologique, 23, 1296-1309.
[20] Rodger, A.J., Jolley, D., Thompson, S.C., Lanigan, A. and Crofts, N. (1999) The Impact of Diagnostic of Hepatitis C Virus on Quality of Life. Hepatology, 30, 1299-1301.
[21] Obhrai, J., Hall, Y. and Anand, B.S. (2001) Assessment of Fatigue and Psychologic Disturbances in Patients with Hepatitis C Virus Infection. Journal of Clinical Gastroenterology, 32, 413-417.

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