Efferocytosis in Retinoblastoma


Retinoblastoma has varied presentations. As age advances in retinoblastoma, the undifferentiated tumour is the common appearance. Apoptosis in retinoblastoma in an untreated case can give us a clue about the tumour biology. Efferocytosis in intraocular tumour is a new concept which was seen in an enucleated eyeball specimen in a 4-year-old boy. Effective efferocytosis can be conceptualized for new pharmacodynamics application for anti-cancer drugs. We present a rare case of retinoblastoma with efferocytosis in retinal pigment epithelium and interesting apoptotic changes.

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D. Das, H. Bhattacharjee, K. Bhattacharjee, P. Tahiliani, P. Bhattacharyya, M. Barman, S. Barthakur, P. Deka, A. Deka and R. Paul, "Efferocytosis in Retinoblastoma," Journal of Cancer Therapy, Vol. 4 No. 9, 2013, pp. 1443-1447. doi: 10.4236/jct.2013.49172.

Conflicts of Interest

The authors declare no conflicts of interest.


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