Efferocytosis in Retinoblastoma

DOI: 10.4236/jct.2013.49172   PDF   HTML     2,879 Downloads   4,267 Views   Citations


Retinoblastoma has varied presentations. As age advances in retinoblastoma, the undifferentiated tumour is the common appearance. Apoptosis in retinoblastoma in an untreated case can give us a clue about the tumour biology. Efferocytosis in intraocular tumour is a new concept which was seen in an enucleated eyeball specimen in a 4-year-old boy. Effective efferocytosis can be conceptualized for new pharmacodynamics application for anti-cancer drugs. We present a rare case of retinoblastoma with efferocytosis in retinal pigment epithelium and interesting apoptotic changes.

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D. Das, H. Bhattacharjee, K. Bhattacharjee, P. Tahiliani, P. Bhattacharyya, M. Barman, S. Barthakur, P. Deka, A. Deka and R. Paul, "Efferocytosis in Retinoblastoma," Journal of Cancer Therapy, Vol. 4 No. 9, 2013, pp. 1443-1447. doi: 10.4236/jct.2013.49172.

Conflicts of Interest

The authors declare no conflicts of interest.


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