Immunosuppressive therapy in pancreas and islet transplant: Need for simultaneous assessment of insulin sensitivity and secretion


Diabetes mellitus is a metabolic disease possible to treat via pancreas/islet transplantation but most immunosuppressive drugs are diabetogenic. In this letter, we review current up to date methods to assess insulin action and secretion (using the surrogate indexes) suggesting their use in large studies in populations of pancreas/ islets transplanted patients.

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Benedini, S. , Caumo, A. , Terruzzi, l. and Luzi, L. (2013) Immunosuppressive therapy in pancreas and islet transplant: Need for simultaneous assessment of insulin sensitivity and secretion. Journal of Diabetes Mellitus, 3, 156-160. doi: 10.4236/jdm.2013.33024.

Conflicts of Interest

The authors declare no conflicts of interest.


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