Behavior of Motile Sperm in Taylor-Couette Flow: Effect of Shear Stress on the Behavior of Motile Sperm


Infertility is often cited as one of the causes of a declining birthrate, which has become a serious social problem in recent years. Processes by which motile sperm can be safely and easily sorted are therefore important for infertility treatment. Therefore, as a new sorting method, microfluidic sperm sorter using the microfluidic system has been developed. To improve more separation efficiency of this device, it is necessary to know the behaviors of motile sperm in the microchannel where the sperm undergo shear flow. The previous study implied the necessity of the modeling of motile sperm in the shear flow. In the present study, therefore, we experimentally investigated the behavior of the motile sperm in the Taylor-Couette flow using PTV (Particle Tracking Velocimetry) method. The experimental results showed that the ascent of the shear stress led to the increase in the sperm velocity, and the direction of the sperm velocity was opposite to that of the flow.

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Y. Hayamizu, T. Hyakutake, K. Matsuura, S. Yanase, S. Morita, S. Ohtsuka and T. Gonda, "Behavior of Motile Sperm in Taylor-Couette Flow: Effect of Shear Stress on the Behavior of Motile Sperm," Open Journal of Fluid Dynamics, Vol. 3 No. 2A, 2013, pp. 9-13. doi: 10.4236/ojfd.2013.32A002.

Conflicts of Interest

The authors declare no conflicts of interest.


[1] E. V. Younglai, D. Holt, P. Brown, A. Jurisicova and R. F. Casper, “Sperm Swim-Up Techniques and DNA Fragmentation,” Human Reproduction, Vol. 16, No. 9, 2001, pp. 1950-1953. doi:10.1093/humrep/16.9.1950
[2] S. Smith, S. Hosid and L. Scott, “Use of Postseparation Sperm Parameters to Determine the Method of Choice for Sperm Preparation for Assisted Reproductive Technology,” Fertility and Sterility, Vol. 63, No. 3, 1995, pp. 591-597.
[3] B. S. Cho, T. G. Schuster, X. Zhu, D. Chang, G. D. Smith and S. Takayama, “Passively Driven Integrated Microfluidic System for Separation of Motile Sperm,” Analytical Chemistry, Vol. 75, No. 7, 2003, pp. 1671-1675. doi:10.1021/ac020579e
[4] T. G. Schuster, B. S. Cho, L. M. Keller, S. Takayama, and G. D. Smith, “Isolation of Motile Spermatozoa from Semen Samples Using Microfluidics,” Reproductive Bio-Medicine, Vol. 7, No. 1, 2003, pp. 75-81. doi:10.1016/S1472-6483(10)61732-4
[5] T. Hyakutake, Y. Hashimoto, S. Yanase, K. Matsuura and K. Naruse, “Application of a Numerical Simulation to Improve the Separation Efficiency of a Sperm Sorter,” Biomedical Microdevices, Vol. 11, No. 1, 2009, pp. 25-33. doi:10.1007/s10544-008-9207-2
[6] H. Schlicting, “Boundary Layer Theory,” 7th Edition, McGraw-Hill Pub. Co., New York, 1987, pp. 525-529.
[7] D. J. Smith, E. A. Gaffney, H. Gadelha, N. Kapur and J. C. Kirkman-Brown, “Bend Propagation in the Flagella of Migrating Human Sperm, and Its Modulation by Viscosity,” Cell Motility and the Cytoskeleton, Vol. 66, No. 4, 2009, pp. 220-236. doi:10.1002/cm.20345

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