Tissue induction, the relationship between biomaterial’s microenvironment and mesenchymal stem cell differentiation

DOI: 10.4236/jbise.2013.61011   PDF   HTML   XML   4,567 Downloads   6,913 Views   Citations


Mesenchymal stem cells (MSCs) have been recognized as the best candidate for tissue engineering, while the mechanism of biomaterial-induced MSCs differentiation is not well understood. Most of research has been focused on chemical signaling of biomaterial in the past, but a variety of non-chemical signals were also proved to play essential roles in cellular behaviors. In this paper, we reviewed the current reports about the effects of different kinds of biomaterial signals on MSCs differentiation.

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Xu, W. , Liao, X. , Zhang, L. and Liu, B. (2013) Tissue induction, the relationship between biomaterial’s microenvironment and mesenchymal stem cell differentiation. Journal of Biomedical Science and Engineering, 6, 85-91. doi: 10.4236/jbise.2013.61011.

Conflicts of Interest

The authors declare no conflicts of interest.


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