Inorganic Molecularly Imprinted Polymer by Sol-Gel Process for Recognition of Caffeine


A molecularly imprinted polymer (MIP) was formed using an inorganic polymer by a sol-gel process. The monomers which were used to synthesize the inorganic polymer were tetraethoxysilane (TEOS), triethoxymethylsilane (MTES), and triethoxyphenylsilane (PTES). Caffeine was chosen as a template for the molecular imprinting, and theophylline was chosen as the analogous counterpart compound. The discriminating ability of the synthesized MIP to these two-compounds was estimated in this study. The MIP showed the highest discriminating ability when the ratio of TEOS:MTES: PTES in the synthesis of the inorganic polymer was 1:1:3, the reaction temperature was 50?C, and the pH of the reaction system was ~6.5.

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M. Shin, Y. Shin and J. Shin, "Inorganic Molecularly Imprinted Polymer by Sol-Gel Process for Recognition of Caffeine," Open Journal of Organic Polymer Materials, Vol. 3 No. 1, 2013, pp. 1-5. doi: 10.4236/ojopm.2013.31001.

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The authors declare no conflicts of interest.


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