The Long Magenstrasse with pyloroplasty as functional gastric bypass: 6-years experience, 308 operations
Carlo Vassallo, Giovanni Berbiglia, Matteo Carena
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DOI: 10.4236/health.2010.28138   PDF    HTML     5,355 Downloads   10,386 Views   Citations

Abstract

Background: The Long Magenstrasse with py-loroplasty as functional Gastric Bypass (briefly LMGBP) procedure for morbid obesity may re- duce the incidence of side effects associated with gastric restrictive and malabsorptive sur- gery, particularly on quality of life and long-term nutritional insufficiency. In follow-up to pre- liminary findings in 34 patients, we report the results of an additional 274 LMGBPs performed over the past 3 years. Methods: Between October 2003 and 2009, 308 patients were treated with the LMGBP. 149 patients underwent open procedures; 74, hand-assisted laparoscopic surgery (HALS); and 85 were operated laparo-scopically. 17% had ≥ 125 mg/dl glycemia, 43% sleep apnea, 38% hyperlipidemia, 12% hyperuricemia, and 58% arterial hypertension under treatment. Results: The mean BMI of 256 pre-operatively normoglycemic patients at 1 year was 29 (range 26-31); 27 (25-30) in 45 patients at 3 years; and 27.5 (26-30) in 12 patients at 5 years. Mean BMI of 53 preoperatively hyperglycemic patients (≥ 125 mg/dl) at 1 year (21 patients) was 32 (29-34), and at 3 years (9 patients), 32.5 (30- 33). 15 patients with preoperative type 2 diabetes under oral treatment required no therapy 3-6 months after surgery. Patients reported considerable appetite reduction with rapid satiety but maintained good nutrition with no supplementation. There was no mortality. Conclusions: Safe and effective sustained weight loss, positive metabolic changes, and appetite diminution with rapid satiety were seen after LMGBP.

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Vassallo, C. , Berbiglia, G. and Carena, M. (2010) The Long Magenstrasse with pyloroplasty as functional gastric bypass: 6-years experience, 308 operations. Health, 2, 935-940. doi: 10.4236/health.2010.28138.

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1] Baltazar, A., Bou, R., Cipagauta, L.A., et al. (1995) “Hy-brid” bariatric surgery: Biliopancreatic diversion and duodenal swich-preliminary experience. Obesity Surgery, 5(4), 419-423.
[2] Bastaroli, E., Della Valle, A., Vassallo, C., et al. (1993) Reflections on 4 years’ activity of an interdisciplinary center for the treatment of obese patients. Obesity Surgery, 3(3), 285-288.
[3] Marceau, P., Biron, S., Bourque, R.A., et al. (1992) Biliopancreatic diversion with a new type of gastrectomy. Obesity Surgery, 3(1), 29-35.
[4] Vassallo, C., Andreoli, M., La Manna, A., et al. (2001) 60 reoperations on 890 patients after gastric restrictive sur-gery. Obesity Surgery, 11(6), 752-756.
[5] Vassallo, C., Negri, L., Della Valle, A., et al. (1999) Di-vided vertical banded gastroplasty either for correction or as a first-choice operation. Obesity Surgery, 9(2), 177- 179.
[6] Vassallo, C., Negri, L, Berbiglia, G., et al. (2004) Bilio- pancreatic diversion with transitory gastric restriction and duodenal bulb preservation: 88 patients since 1992. Obesity Surgery, 14(6), 773-776.
[7] Johnston, D., Dachtler, J., Sue-Ling, H., et al. (2003) The Magenstrasse and Mill operation for morbid obesity. Obesity Surgery, 13(1), 10-16.
[8] Johnston, D. and Sue-Ling, H. (1995) Surgical treatment of morbid obesity. In: Cushieri, A., Moosa, A.R., Giles, G.R., Eds., Essential Surgical Practice. Butterworth- Heinemann, London, 1036-1044.
[9] Robinson, J., Sue-Ling, H. and Johnston, D. (2006) The Magenstrasse and Mill procedure can be combined with a Roux-en-Y gastric bypass to produce greater and sus-tained weight loss. Obesity Surgery, 16(7), 891-896.
[10] Vassallo, C., Berbiglia, G., et al. (2007) The Long Ma-genstrasse and Mill operation with pyloroplasty: Pre-liminary results. Obesity Surgery, 17(8), 1080-1083.
[11] Carmichael, A.R., Sue-Ling, H.M. and Johnston, D. (2001) Quality of life after the Magenstrasse and Mill procedure for morbid obesity. Obesity Surgery, 11(6), 708-715.
[12] Mason, E.E. (2005) The mechanisms of surgical treat- ment of type 2 diabetes. Obesity Surgery, 15(4), 459-461.
[13] Rubino, F., Forgione, A., Cummings, D.E., et al. (2006) The mechanism of diabetes control after gastrointestinal bypass surgery reveals a role of the proximal small intes-tine in the pathophysiology of type 2 diabetes. Annals of Surgery, 244(5), 741-749.
[14] Scopinaro, N., Papadia, F., et al. (2008) A comparison of a personal series of biliopancreatic diversion and litera-ture data and gastric bypass help to explain the mecha-nisms of resolution of type 2 diabetes by the two opera-tions. Obesity Surgery, 18(8), 1035-1038.
[15] Siewert, J.R. and Muller, C.. (1983) Terapia chirurgica dell’ulcera duodenale non complicata. In: Allg?wer, M., Harder, F., Hollender, L.F., Peiper, H.J. and Siewert, J.R., Eds. Trattato di Gastroenterologia Chirurgica. Antonio Delfino Editore, Rome, 2, 463-466.
[16] Amdrup, E. and Jensen, H.E. (1973) One hundred pa-tients five years after selective gastric vagotomy and drainage for duodenal ulcer. Surgery, 74, 321-325.
[17] Goligher, J.C., Pulvertaft, C.N., et al. (1972) Five to eight years results of truncal vagotomy and pyloroplasty for duodenal ulcer. British Medical Journal, 1(5791), 7-13.
[18] Johnston, D., Humphrey, C.S., et al. (1970) Should the gastric antrum be vagally denervated if it is well drained and in the acid stream? British Journal of Surgery, 58(10), 725-731.
[19] Thompson, J.D. and Galloway, J.B.W. (1979) Vagotomy and pyloric dilatation in chronic duodenal ulceration. British Medical Journal, 1(6176), 1453-1455.
[20] Taylor, T.V., Lythgoe, J.P., et al. (1990) Anterior lesser curve seromyotomy and posterior truncal vagotomy versus truncal vagotomy and pyloroplasty in the treatment of chronic duodenal ulcer. British Journal of Surgery, 77, 1007-1009.
[21] Almogy, G. Crookes, P.F., Anthone, G.I., et al. (2004) Longitudinal gastrectomy as a treatment for the high-risk super-obese patient. Obesity Surgery, 14(4), 492-497.
[22] Morínigo, R., Lacy, A.M., et al. (2006) GLP-1 and changes in glucose tolerance following gastric bypass surgery in morbidly obese subjects. Obesity Surgery, 16(12), 1594-1601.
[23] Conce, M.E., Cottam, D. and Esplen, J. (2006) Is ghrelin the culprit for weight loss after gastric bypass surgery? A negative answer. Obesity Surgery, 16(7), 870-878.
[24] Frühbeck, G., Diaz-Caballero, A., Gil, M.J., et al. (2004) The decrease in plasma ghrelin concentrations following surgery depends on the functional integrity of the fundus. Obesity Surgery, 14(5), 606-612.
[25] Garcia-Fuentes, E., Garrido-Sanchez, L., et al. (2008) Different effect of laparoscopic Roux-en-Y gastric by-pass and open biliopancreatic diversion of Scopinaro on serum PYY and ghrelin levels. Obesity Surgery, 18, 1424-1429.
[26] Roth, C.L., Reinehr, T., et al. (2009) Ghrelin and obes-tatin levels in severely obese women before and after weight loss after Roux-en-Y gastric bypass surgery. Obesity Surgery, 19(1), 29-35.
[27] Reinehr, T., Roth, C.L., et al. (2007) Peptide YY and glucagon-like peptide-1 in morbidly obese patients be-fore and after surgically induced weight loss. Obesity Surgery, 17(12), 1571-1577.
[28] Reavis, K.M., Hinojosa, M.W., et al. (2008) Single lapar- oscopic incision transabdominal surgery sleeve gastrec-tomy. Obesity Surgery, 18(11), 1492-1494.
[29] Schweitzer, D.H. and Posthuma, E.F. (2008) Prevention of vitamin and mineral deficiencies after bariatric surgery: Evidence and algorithms. Obesity Surgery, 18(11), 1485- 1488.

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