Postpartum fatal cerebral vein thrombosis: A case report and review

DOI: 10.4236/ojcd.2012.21001   PDF   HTML   XML   3,700 Downloads   8,708 Views   Citations

Abstract

Background: Cerebral vein thrombosis, is an emergent condition presenting with a variety of symptoms ranging from isolated headache to profound coma. Case Presentation: We present the case of a previously healthy young woman on the 18th postpartum day admitted into our hospital with a persistent headache for three days followed by seizures and coma. Magnetic Resonance Angiography revealed superior sagittal sinus and right transverse sinus thrombosis. Despite supportive measures and anticoagulation, the patient died because of uncontrolled increase in intracranial pressure. Conclusion: The possibility of cerebral vein thrombosis should be considered in all women with brain dysfunction during the puerperium.

Share and Cite:

Kontogiorgi, M. , Kalodimou, V. , Kollias, S. , Exarchos, D. , Nanas, S. , Ghiatas, A. and Routsi, C. (2012) Postpartum fatal cerebral vein thrombosis: A case report and review. Open Journal of Clinical Diagnostics, 2, 1-3. doi: 10.4236/ojcd.2012.21001.

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1] Stam, J. (2005) Thrombosis of the cerebral veins and sinuses. The New England Journal of Medicine, 352, 1791-1798. doi:10.1056/NEJMra042354
[2] Bousser, M.G. (2000) Cerebral venous thrombosis: diagnosis and management. Journal of Neurology, 247, 252-258. doi:10.1007/s004150050579
[3] Crassard, I. and Bousser, M.G. (2004) Cerebral venous thrombosis. Journal of Neuro-Ophthalmology, 24, 156-163. doi:10.1097/00041327-200406000-00011
[4] Cantou, C. and Barinagarrementeria, F. (1993) Cerebral venous thrombosis associated with pregnancy and puerperium: Review of 67 cases. Stroke, 24, 1880-1884. doi:10.1161/01.STR.24.12.1880
[5] Mas, J.L. and Lamy, C. (1998) Stroke in pregnancy and the puerperium. Journal of Neurology, 245, 305-313. doi:10.1007/s004150050224
[6] Ferro, J.M., Canhao, P., Starn, J., Bousser, M.G. and Barinagarrementeria, F. (2004) Prognosis of cerebral vein and dural sinus throm-bosis: results of the international study on cerebral vein and dural sinus thrombosis (ISCVI). Stroke, 35, 664-670. doi:10.1161/01.STR.0000117571.76197.26
[7] Ozsvath, R.R., Casey, S.O., Lustrin, E.S., Alberico, R.A., Has-sankhani, H. and Patel, M. (1997) Cerebral venography: Comparison of CT and MR projection venography. American Journal of Roentgenology, 169, 1699-1707.
[8] Einhaupl, K., Stam, J., Bousser, M.G., De Bruijn, S.F.T.M., Ferro, J.M., Martinelli, M. and Masuhr, F. (2010) EFNS guideline on the treatment of cerebral venous and sinus thrombosis in adult patients. European Journal of Neurology, 17, 1229-1235. doi:10.1111/j.1468-1331.2010.03011.x
[9] Lanska, D.J. and Kryscio, R.J. (2000) Risk factors for peripartum and postpartum stroke and intracranial venous thrombosis. Stoke, 31, 1274-1282.
[10] Chan, K.H., Cheung, R.T.F., Liu, W.M., Mak, W. and Ho, S.L. (2005) Cerebral ve-nous thrombosis in a gentleman presenting with fever, convulsion and frontotemporal haemorrhages. Journal of Clinical Neuroscience, 12, 186-188. doi:10.1016/j.jocn.2004.03.013
[11] Pannke, T.S. (1991) Cerebral dural sinus thrombosis. Annals of Emergency Medicine, 20, 813-816. doi:10.1016/S0196-0644(05)80849-2
[12] Nazziola, E. and Elkind, M.S. (2003) Dural sinus thrombosis pre-senting three months postpartum. Annals of Emergency Medicine, 42, 592-595. doi:10.1067/S0196-0644(03)00389-5

  
comments powered by Disqus

Copyright © 2020 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.