Author(s)

Ruchee Phonchai^1,2, Bunchob Ubonsaen³, Supaluk Brameld⁴, Pimjai Naigovit²

¹Neuroscience Research Center, Institute of Molecular Biosciences, Mahidol University, Nakhon Pathom, Thailand.
²LBM Stem Cell Research Unit, Life Balance Methodology Co, Ltd., Bangkok, Thailand.
³Sangkhom Hospital, Nongkhai Provincial Health Office, Nongkhai, Thailand.
⁴National Institute of Health, Ministry of Public Health, Bangkok, Thailand.

Hyperpigmentation is a common skin problem in a woman. Prolonging topical use of skin whitening may cause hyperpigmentation such as ochronosis whose condition is a challenge for treatment. An aqueous human placenta extract (RGF®) contains bioactive therapeutic molecules. There is evidence of human placenta extract showing that melanin synthesis is inhibited by placenta extract in melanocytes. We first reported the case of the hyperpigmentation improvement following face skin mesotherapy human placenta extract treatment.

Hyperpigmentation, Human Placenta Extract, Mesotherapy

Phonchai, R. , Ubonsaen, B. , Brameld, S. and Naigovit, P. (2019) Case Report: Improvement of Long Lasting Hyperpigmentation by Aqueous Human Placenta Extract (Reju Growth Factor, RGF®) Treatment. Journal of Cosmetics, Dermatological Sciences and Applications, 9, 125-128. doi: 10.4236/jcdsa.2019.92011.