Journal of Biosciences and Medicines

Volume 4, Issue 9 (September 2016)

ISSN Print: 2327-5081   ISSN Online: 2327-509X

Google-based Impact Factor: 0.80  Citations  

Long-Term Continuous Light Exposure Affects Body Weight and Blood Glucose Associated with Inflammation in Female Rats

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DOI: 10.4236/jbm.2016.49002    1,581 Downloads   2,944 Views  Citations

ABSTRACT

Studies have indicated that night lights interfere with the circadian rhythm in the human body and threaten human health. Our previous studies indicated that continuous light exposure severely damages the reproductive endocrine system of female rats resembles polycystic ovary syndrome in women. In this study, we used the continuous measurement method to observe changes in the basal physiological indicators of female rats in an abnormal light exposure environment. Our study results indicated that in female rats: 1) the body temperature first continuously and gradually increased followed by a gradually decrease; 2) the increase in body weight slowed down at the late stage of the experimental process; 3) the random blood glucose level increased, and the fasting serum insulin level decreased; and 4) the serum C-reactive protein level increased. Our study investigated for the first time the correlation between the duration of continuous light exposure in female rats and the continuously measured basal physiological indicators and preliminarily discussed the effect of continuous light exposure on female basal metabolism and the possible inflammation mechanism. We propose that long-term continuous exposure to night lights in females severely damages their immune and metabolic systems.

Share and Cite:

Kang, X. , Jia, L. , Zhang, X. , Li, Y. , Chen, Y. , Shen, X. and Wu, Y. (2016) Long-Term Continuous Light Exposure Affects Body Weight and Blood Glucose Associated with Inflammation in Female Rats. Journal of Biosciences and Medicines, 4, 11-24. doi: 10.4236/jbm.2016.49002.

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