Author(s)

Adoum Fouda Abderrazzack^1,2, Mounerou Salou^3,4*, Akouda Patassi⁵, Degninou Yehadji⁶, Yaovi Ameyapoh^2*

¹Service de Laboratoire et médicaments du Programme Sectoriel de lutte contre le sida et les Infections Sexuellement Transmissibles, N’djamena, Tchad.
²Laboratoire de microbiologie et de controle de qualité de denrées alimentaires, Ecole Supérieure des Techniques Biologiques et Alimentaires, University of Lomé, Lomé, Togo.
³Département des sciences fondamentales, Faculty of Health Science, University of Lomé, Laboratory of Microbiology CHU Sylvanus OLIMPYO, Lomé, Togo.
⁴Centre de biologie moléculaire et d’immunologie, FSS/UL, Lomé, Togo.
⁵Service des maladies infectieuses, CHU Sylvanus OLIMPYO, Lomé, Togo.
⁶Ministry of Health, Lomé, Togo.

A cross-sectional study was conducted at the “Centre de l’Appui Psycho-Médico-Social (APMS)” which is a centre for Psychological and Medical Support in N'Djamena (Chad) from January to March 2014. The aim of this study was to evaluate the correlation between asymptomatic bacteriuria (ASB) and viral load level and CD4 count in seventy-six (76) HIV-1 infected pregnant women on antiretroviral therapy (ART). Urine culture and bacteria identification were performed by using a chromogenic culture medium (UriselectR4). T CD4+ lymphocytes count and viral load measurement were done respectively on PIMATM test and Abbott m2000 RealTime HIV-1. In this study, 25 (32.9%) pregnant women were carrying ASB and major bacteria; Escherichia coli and Streptococcus agalactiae known to cause neonatal meningitis to newborns were identified. Bacteria were isolated mainly in women with CD4 lymphocytes < 200 cells/mm3 (60%) (15/25) and a viral load > 3log (70%) (19/25). Besides the prevention of mother to child transmission of HIV, which remains a goal, it is important to prevent also the transmission of other microorganisms causing neonatal infections. Our findings support the needs to do bacteriological analysis of urine in every HIV-infected pregnant woman at least in late pregnancy.

Pregnant Women, Asymptomatic Bacteriuria, Lymphocyte CD4, Viral Load

Abderrazzack, A. , Salou, M. , Patassi, A. , Yehadji, D. and Ameyapoh, Y. (2015) Correlation between Asymptomatic Bacteriuria and HIV-1 Viral Load Level and CD4 Count in Pregnant Women on Antiretroviral Therapy in N’djamena (Chad). World Journal of AIDS, 5, 308-312. doi: 10.4236/wja.2015.54033.