One-Pot Three Component Domino Reaction for the Synthesis of Novel Isoxazolo[2,3-c][1,3,5]Thiadiazepin-2-Ones Catalyzed by PTSA—A Green Chemistry Approach - Green and Sustainable Chemistry

GSC > Vol.5 No.3, August 2015

Volume 5, Issue 3 (August 2015)

ISSN Print: 2160-6951 ISSN Online: 2160-696X

Google-based Impact Factor: 1.8 Citations

One-Pot Three Component Domino Reaction for the Synthesis of Novel Isoxazolo[2,3-c][1,3,5]Thiadiazepin-2-Ones Catalyzed by PTSA—A Green Chemistry Approach ()

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DOI: 10.4236/gsc.2015.53014 5,336 Downloads 7,007 Views Citations

Author(s)

Eligeti Rajanarendar^*, Paka Venkateshwarlu, Saini Rama Krishna, Kundur Govardhan Reddy, Kammari Thirupathaiah

Affiliation(s)

Department of Chemistry, Kakatiya University, Warangal, India.

ABSTRACT

The synthesis of novel isoxazolo[2,3-c][1,3,5]thiadiazepin-2-ones has been achieved in excellent yields by one-pot three-component Domino reaction without the production of toxic waste products by using p-toluene sulfonic acid (PTSA) as a Lewis acid catalyst. PTSA plays a crucial role in the success of the reaction, as well as for increasing reaction rate.

KEYWORDS

Multi-Component Green Synthesis, Isoxazolo[2, 3-c][1, 3, 5]Thiadiazepin-2-Ones, PTSA

Share and Cite:

Rajanarendar, E. , Venkateshwarlu, P. , Krishna, S. , Reddy, K. and Thirupathaiah, K. (2015) One-Pot Three Component Domino Reaction for the Synthesis of Novel Isoxazolo[2,3-c][1,3,5]Thiadiazepin-2-Ones Catalyzed by PTSA—A Green Chemistry Approach. Green and Sustainable Chemistry, 5, 107-114. doi: 10.4236/gsc.2015.53014.

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