Considering characteristic of mHealth communication and problems of existing methods, this paper presents a real-time communication method for mHealth based on extended XMPP protocol. The method can maintain the role status efficiently and reduce data latency during the communication process. Meanwhile, it can be extended flexibly to meet increasing communication demands of mHealth services. Furthermore, a system framework is presented to support telemonitoring scene. Finally, system implementation and feasibility tests verify the effectiveness of the method and framework.