Diagnostic dilemma: metastatic bone malignancy or primary hyperparathyroidism with brown tumor - Open Journal of Internal Medicine

OJIM > Vol.3 No.2, June 2013

Open Journal of Internal Medicine

Volume 3, Issue 2 (June 2013)

ISSN Print: 2162-5972 ISSN Online: 2162-5980

Google-based Impact Factor: 0.69 Citations

Diagnostic dilemma: metastatic bone malignancy or primary hyperparathyroidism with brown tumor ()

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DOI: 10.4236/ojim.2013.32015 4,611 Downloads 6,691 Views Citations

Author(s)

Esra Hatipoglu, Ahmet Emre Eskazan, Ozlem Celik, Fatih Kantarci, Pinar Kadioglu

Affiliation(s)

Department of Radiology, Cerrahpasa Medical School, University of Istanbul, Istanbul, Turkey.
Division of Endocrinology and Metabolism, Department of Internal Medicine, Cerrahpasa Medical School, University of Istanbul, Istanbul, Turkey.
Division of Hematology, Department of Internal Medicine, Cerrahpasa Medical School, University of Istanbul, Istanbul, Turkey.

ABSTRACT

Multiple osteolytic lesions are usually associated with metastatic involvement of the bone. However metabolic bone diseases should also take their place in differential diagnosis. Here, we describe a primary hyperparathyroidism case with full-blown osteolytic lesions wich was diagnosed at first sight with having metastatic bone involvement. PET CT scan and laboratory results excluded a metastatic bone malignancy. Elevated serum calcium of 13.16 mg/dl, decreased serum phoshorus of 1.4 mg/dl and high intact-PTH level of 1054.7 pg/ml pointed out primary hyperparathyroidism. Sonographic examination revealed two adenomas of 2.9 × 3.3 mmand 3.3 ×2.7 mmin the left superior and right inferior parathyroid glands, respectively. Scintigraphy confirmed the presence of adenoma on the left.

KEYWORDS

Brown Tumor; Hyperparathyroidism; Metastatic Bone Disease

Share and Cite:

Hatipoglu, E. , Eskazan, A. , Celik, O. , Kantarci, F. and Kadioglu, P. (2013) Diagnostic dilemma: metastatic bone malignancy or primary hyperparathyroidism with brown tumor. Open Journal of Internal Medicine, 3, 60-62. doi: 10.4236/ojim.2013.32015.

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