Author(s)

Ahmed Dervis

Department of Orthopaedic Surgery, Kanuni Sultan Suleyman Training and Research Hospital, Istanbul, Türkiye.

Background: Osteosarcoma is the most common primary malignant bone tumor in children and young adults. Pulmonary metastasis is frequent, but pleural effusion is an unusual and challenging concomitant finding. We present a case of osteosarcoma with pleural effusion, managed successfully with multimodal therapy, and no recurrence after 3 years of follow-up. Case Presentation: We report a 17-year-old boy with osteosarcoma of the distal femur and reactive left-sided pleural effusion. The patient underwent thoracentesis followed by neoadjuvant chemotherapy, limb-salvage surgery, and adjuvant chemotherapy. The effusion resolved and did not recur. Conclusion: This case highlights that pleural effusion may accompany bone tumors even without metastasis, and that multidisciplinary management can achieve excellent outcomes.

Osteosarcoma, Pleural Effusion, Adolescent, Bone Tumor, Case Report, Limb-Salvage Surgery

Dervis, A. (2025) Curative Outcome of Osteosarcoma with Associated Pleural Effusion: A Case Report
—Bone Tumor with Pleural Effusion in an Adolescent. Open Journal of Respiratory Diseases, 15, 188-192. doi: 10.4236/ojrd.2025.154014.