Author(s)

Chenchen Zhang, Bing Wang^*

Intensive Care Unit, Jingzhou Hospital Affiliated to Yangtze University, Jingzhou, China.

Neonatal respiratory distress syndrome (NRDS) is a prevalent and critical condition in the neonatal period, where early and accurate diagnosis is crucial for timely intervention and improved prognosis. In recent years, lung ultrasound (LUS) has emerged as a non-invasive, portable, repeatable, and radiation-free imaging modality, demonstrating significant advantages in the diagnosis and assessment of NRDS. LUS enables bedside, real-time monitoring of pulmonary lesion changes. By identifying characteristic sonographic findings—including absence of lung sliding, disappearance of A-lines, increased B-lines, and irregular pleural lines, LUS facilitates visual assessment of pulmonary ventilation disorders. Studies have shown that LUS offers high sensitivity and specificity in diagnosing NRDS, with diagnostic accuracy comparable to or exceeding that of chest X-ray. Additionally, LUS effectively evaluates disease severity, informs clinical decision-making, and assists in prognosis prediction. This review summarizes recent advances in the application of lung ultrasound for the diagnosis of neonatal respiratory distress syndrome.

Neonatal Respiratory Distress Syndrome, Lung Ultrasound, Diagnosis, Application Progress

Zhang, C.C. and Wang, B. (2025) Advances in the Application of Lung Ultrasound in the Diagnosis of Neonatal Respiratory Distress Syndrome. Journal of Biosciences and Medicines, 13, 226-236. doi: 10.4236/jbm.2025.1311016.