Author(s)

Franck Auguste Hermann Adémayali Ido^1*, Souleymane Ouattara², Rakiswendé Alexis Ouedraogo³, Ibrahim Savadogo⁴, Aimé Sosthène Ouedraogo⁵, Assita Lamien-Sanou⁶, Olga Melanie Lompo⁶

¹Department of Anatomy and Pathological Cytology, CHU Tengandogo, Ouagadougou, Burkina Faso.
²Department of Anatomy and Pathological Cytology, CHU-R Fada, N’gourma Burkina Faso.
³Department of Histo-Embryo-Cytogenetics, Bogodogo University Hospital, Ouagadougou, Burkina Faso.
⁴Department of Anatomy and Pathological Cytology, CHU-R of Ouahigouya, Ouahigouya, Burkina Faso.
⁵Department of Anatomy and Pathological Cytology, CHU Bogodogo, Ouagadougou, Burkina Faso.
⁶Department of Anatomy and Pathological Cytology, CHU Yalgado Ouédraogo, Ouagadougou, Burkina Faso.

We report four observations of inflammatory fibroid polyps, including a rare case of appendicular localization. Two of our patients were female and two were male. They were aged 19, 24, 39, and 4 years, respectively. These were four cases discovered on surgical specimens after acute digestive episodes requiring laparotomy. Macroscopically, they were polypoid masses that developed at the expense of the submucosa. The polyp size ranged from 9 to 4 cm on the long axis. Microscopically, the masses were composed of spindle and/or star-shaped cells in a richly vascularized fibromyxoid chorion, reworked by a polymorphic infiltrate of predsominantly eosinophilic polynuclear cells. Immunohistochemically, tumor cells expressed high levels of CD34 with a very low Ki67 proliferation index. Inflammatory adenoid polyp is a rare benign lesion that can affect all segments of the digestive tract. Its pathogenesis is poorly understood and remains controversial. Its diagnosis can be difficult, especially on endoscopic biopsy, leading to its discussion with inflammatory lesions and certain spindle cell tumors of the digestive tract. It is treated surgically, with a good prognosis and no recurrence after total excision.

Intestinal, Inflammatory, Fibroid, Polyp

Ido, F.A.H.A., Ouattara, S., Ouedraogo, R.A., Savadogo, I., Ouedraogo, A.S., La-mien-Sanou, A. and Lompo, O.M. (2025) Inflammatory Fibroid Polyp: About Four Observations Including an Appendicular Localization. Open Journal of Pathology, 15, 126-135. doi: 10.4236/ojpathology.2025.153012.