Author(s)

David Fernando Ortiz-Pérez^1,2,3, Mario Enrique Montoya-Jaramillo^1,3, Jorge Luis Acosta-Muñoz^4,5, Jhon Alexander Pérez-Sanmiguel⁶, Miguel Correa-Cotuá⁷, Bety Luz Díaz-Verbel⁷, Santiago José González-Manzur⁷, Jean Carlos Meza-Castillo⁸, Ricardo Andres Donado-Botero^1,2,3

¹Department of Internal Medicine, Cartagena del Mar Medical Center, Cartagena, Colombia.
²Internal Medicine, University of Sinú, Cartagena, Colombia.
³Medistar, Internal Medicine Research Group, Cartagena, Colombia.
⁴Internal Medicine, Libre University, Barranquilla, Colombia.
⁵Department of Nephrology, Simón Bolívar University, Barranquilla, Colombia.
⁶General Medicine, Rafael Núñez University Corporation, Cartagena, Colombia.
⁷General Medicine, University of Sinú, Cartagena, Colombia.
⁸General Medicine, University of Cartagena, Cartagena, Colombia.

Pulmonary metastases constitute a common and clinically significant complication of various extrathoracic malignancies. This article presents five illustrative cases—three breast carcinomas, one colorectal adenocarcinoma, and an initially occult colonic primary—that exemplifies the biological, clinical, and therapeutic heterogeneity of this entity. All patients exhibited bilateral nodules, mediastinal lymphadenopathy, and, in two cases, malignant pleural effusion. Early integration of palliative care proved essential in scenarios of sepsis or functional frailty. These findings confirm that prognosis depends on tumor biology, extrapulmonary disease burden, and host response, and they underscore the need for an individualized, multidisciplinary approach that combines tumor-directed therapy, symptom control, and comprehensive support.

Pulmonary Metastases, Neoplasms, Radiotherapy, Palliative Care

Ortiz-Pérez, D.F., Montoya-Jaramillo, M.E., Acosta-Muñoz, J.L., Pérez-Sanmiguel, J.A., Correa-Cotuá, M., Díaz-Verbel, B.L., González-Manzur, S.J. and Donado-Botero, R.A. (2025) Seeds in Pulmonary Soil: Brief Review and Presentation of a Multitumoral Pulmonary Metastasis Case Series. Journal of Biosciences and Medicines, 13, 245-254. doi: 10.4236/jbm.2025.136021.