Author(s)

Francis Daniel Nkolo Tolo^1*, Marie Damien Essono², Mahamat Alio Hamit³, Serge Eteme Enama⁴

¹Department of Oral Surgery, Faculty of Medicine and Biomedical Sciences, University of Yaounde I, Yaounde, Cameroon.
²Department of Microbiology, University of Yaounde I, Yaounde, Cameroon.
³Faculty of Human Health Sciences, University of N’Djamena, N’Djamena, Chad.
⁴Department of Animal Biology and Physiology, University of Yaounde I, Yaounde, Cameroon.

Introduction: Fungal infections of the oral and maxillofacial region represent a major clinical challenge in Cameroon. This study aims to analyze the epidemiological characteristics, diagnostic and therapeutic approaches to mycoses encountered in this context. Materials and Method: A systematic review of the literature was carried out, supplemented by a retrospective analysis of 87 cases of fungal infections of the orofacial region managed in three Cameroonian hospitals between 2018 and 2023. Results: The most frequently identified mycoses were candidiasis (58.6%), aspergillosis (17.2%) and mucormycosis (9.2%). A higher prevalence was observed in immunocompromised (43.7%) and diabetic (28.7%) patients. The mycological diagnosis was confirmed in 73.6% of cases. Therapeutic protocols combining surgery and systemic antifungal agents showed a cure rate of 81.6%. Conclusion: Effective management of orofacial fungal infections in Cameroon requires a multidisciplinary approach, early and accurate diagnosis, and therapy adapted to the local context, taking into account available resources and frequent comorbidities.

Management, Fungal Infections, Oral and Maxillofacial Surgery, Cameroon, Literature Review

Nkolo Tolo, F.D., Essono, M.D., Hamit, M.A. and Eteme Enama, S. (2025) Management of Fungal Infections in Oral and Maxillofacial Surgery in Cameroon: Literature Review and Clinical Experience. Open Journal of Stomatology, 15, 129-141. doi: 10.4236/ojst.2025.156012.