Author(s)

Hind Majd^*, Najlae Demnati Sadki, Ouiame El Meliani, Mohammed Tareq Saoudi, Kaoutar Maadin, Lamiae Amaadour, Karima Oualla, Zineb Benbrahim, Samia Arifi, Nawfel Mellas

Hassan II University Hospital of Fez, Fez, Morocco.

Breast metastasis from gastrointestinal cancers is uncommon, accounting for 0.5% to 2% of breast cancer cases. The clinical and radiological manifestations may resemble those of primary breast cancer, making accurate diagnosis challenging. Here, we present the case of a 26-year-old female with breast metastasis from rectal cancer. This report describes the patient’s clinical presentation, diagnostic workup, and management, as well as a review of current literature. The aim of this case report is to highlight a rare clinical presentation, raise awareness of uncommon metastatic sites of rectal cancer, and emphasize the importance of distinguishing between primary and metastatic breast cancer to guide appropriate treatment. Key findings include the rapid progression of the disease, the challenges in management, and the poor prognosis associated with such metastases.

Rectal Cancer, Breast Metastasis, Immunohistochemistry, Colorectal Cancer, Metastatic Disease

Majd, H. , Sadki, N. , Meliani, O. , Saoudi, M. , Maadin, K. , Amaadour, L. , Oualla, K. , Benbrahim, Z. , Arifi, S. and Mellas, N. (2025) Breast Metastases of Rectal Cancer: A Case Report and Review of the Literature. Journal of Cancer Therapy, 16, 178-185. doi: 10.4236/jct.2025.165014.