Author(s)

Kesha Pareshkumar Patel, Terry L. Oroszi

Department of Pharmacology & Toxicology, Boonshoft School of Medicine, Wright State University, Fairborn, OH, USA.

Schizophrenia is a severely impacting serious mental illness that presents numerous difficulties to those who suffer from it, their families, and society. While much effort has been invested in understanding successful treatments, it is still a major issue in public health. This review assesses the advances and issues in the management of schizophrenia in the 21st century, paying special attention to drugs, psychosocial techniques, and connected specialty care. Medications for antipsychotics and psychosocial procedures have shown potential to relieve symptoms and improve functioning, while Recovery-Oriented Care and Psychological Trauma Recovery focus on early diagnosis, combined treatment, and sustained attention. However, many questions remain that need to be answered, including access to care, unmet needs, and discrepancies. Today’s neuroscience research, along with genetic studies and novel therapy options, such as long-acting injectable antipsychotics or telepsychiatry, offers the possibility of further progress being made. Future research exploring fields such as neuroscience, genetics, and implementation science could lead to increasingly effective strategies for people with schizophrenia.

Schizophrenia, Antipsychotics, Psychosocial Interventions, Coordinated Specialty Care, Evidence-Based Models

Patel, K. and Oroszi, T. (2025) Schizophrenia Management Approaches: A Look at Progress and Challenges. World Journal of Neuroscience, 15, 13-34. doi: 10.4236/wjns.2025.151003.