Author(s)

Huijun Z. Ring^*, Ryan Kern

Department of Medicine, Stanford University, California, USA.

The Neuro-Immuno-Endocrine axis coordinates interactions between the nervous, immune, and endocrine systems to maintain physiological homeostasis and respond to internal and external stimuli. Dysregulation of this axis is implicated in chronic stress, inflammation, and a variety of diseases. Zen meditation, a focused and intentional practice rooted in mindfulness, has gained recognition for its profound health benefits. By engaging the Neuro-Immuno-Endocrine axis, Zen meditation supports stress reduction, immune resilience, and hormonal balance. This review explores the interplay between Zen meditation and the Neuro-Immuno-Endocrine axis, emphasizing its neurological, immune, and endocrine impacts. A research question guiding this review is: “How does Zen meditation influence the interconnected components of the Neuro-Immuno-Endocrine axis, and what are the potential mechanisms underlying these effects?” This review hypothesizes that Zen meditation positively impacts the Neuro-Immuno-Endocrine axis through stress-reduction mechanisms that enhance neuroplasticity, reduce systemic inflammation, and balance hormonal pathways. We further discuss how the synergy between Zen meditation and the Neuro-Immuno-Endocrine axis contributes to holistic health and suggest future research directions to optimize its therapeutic applications.

Endocrine Balance, Immune Modulation, Inflammatory Response, Neurological Response, Neuro-Immuno-Endocrine Axis, Stress Reduction, Zen Meditation

Ring, H.Z. and Kern, R. (2024) Zen Meditation and the Neuro-Immuno-Endocrine Axis. Health, 16, 1242-1249. doi: 10.4236/health.2024.1612086.