Author(s)

Yaping Sun, Xianglin Cheng^*, Ke Peng

Department of Neurology, The First Affiliated Hospital of Yangtze University, Jingzhou, China.

Background: Our study aimed to investigate the clinical value of platelet parameters and the number of Monocytes (MONO) in the peripheral blood of patients with Ocular Myasthenia Gravis (OMG). Methods: Fifty patients discharged from the Department of Neurology of the First People’s Hospital of Jingzhou City with the diagnosis of OMG from January 1, 2020, to December 31, 2023, were selected as the experimental group, and healthy medical examiners were selected as the control group during the same period. The differences in peripheral blood mononuclear cell count and platelet-related parameters between the two groups were compared. ROC curves were drawn to analyze the clinical value of the studied indexes in patients with OMG. Results: Patients with OMG had significantly higher monocyte counts and narrower platelet distributions compared with normal adults; further logistic regression analysis revealed that higher monocyte counts and narrower Platelet Distribution Width (PDW) may be independent influences on the occurrence of OMG (p < 0.05), and study with ROC curves suggested that monocyte counts and PDW may have some diagnostic value in the development of OMG may have some diagnostic value. Conclusion: Peripheral blood mononuclear cell count and PDW have some diagnostic value in OMG.

Ocular Myasthenia Gravis, Mononuclear Cell, Platelet Distribution Width

Sun, Y. , Cheng, X. and Peng, K. (2024) Clinical Value of Platelet-Related Parameters and Monocyte Counts in Patients with Oculomotor Myasthenia Gravis. Case Reports in Clinical Medicine, 13, 572-580. doi: 10.4236/crcm.2024.1312067.