Author(s)

Tasmim Adry¹, Nuzhat Tabassum Maisha¹, Md. Abdul Gafur^2*, Suraya Sabrin Soshi³, Maruf Hasan¹

¹Department of Biomedical Engineering, Military Institute of Science and Technology, Dhaka, Bangladesh.
²Pilot Plant and Process Development Center, Bangladesh Council of Scientific and Industrial Research (BCSIR), Dhaka, Bangladesh.
³Department of Mechanical Engineering, Ahsanullah University of Science and Tecnology (AUST), Tejgaong, Dhaka, Bangladesh.

Calcium-based biocomposite materials have a pivotal role in the biomedical field with their diverse properties and applications in combating challenging medical problems. The study states the development and characterization of Calcium-based biocomposites: Hydroxyapatite (HAP), and PVA-Gelatin-HAP films. For the preparation of Calcium-based biocomposites, an unconventional source, the waste material calcite stone, was used as calcium raw material, and by the process of calcination, calcium oxide was synthesized. From calcium oxide, HAP was prepared by chemical precipitation method, which was later added in different proportions to PVA-Gelatin solution and finally dried to form biocomposite films. Then the different properties of PVA/Gelatin/HAP composite, for instance, chemical, mechanical, thermal, and swelling properties due to the incorporation of various proportions of HAP in PVA-Gelatin solution, were investigated. The characterization of the HAP was conducted by X-ray Diffraction Analysis, and the characterization of HAP-PVA-Gelatin composites was done by Fourier Transform Infrared Spectroscopy, Thermomechanical Analysis, Tensile test, Thermogravimetric Differential Thermal Analysis, and Swelling Test. The produced biocomposite films might have applications in orthopedic implants, drug delivery, bone tissue engineering, and wound healing.

Hydroxyapatite, Calcium-Based Biocomposites, PVA-Gelatin Films, Drug Delivery, Bone Tissue Engineering

Adry, T. , Maisha, N. , Gafur, M. , Soshi, S. and Hasan, M. (2024) Development and Characterization of Calcium Based Biocomposites Using Waste Material (Calcite Stones) for Biomedical Applications. Materials Sciences and Applications, 15, 113-135. doi: 10.4236/msa.2024.155009.