Author(s)

Francis Chukwuebuka Ihenetu^*, Sylvester Ifunanya Okorondu, Chinwe Ifenyinwa Chikwendu, Rose Nkechinyere Nwabueze, Ifeoma Ijeoma Anekwe

Department of Microbiology, Federal University of Technology, Owerri, Nigeria.

Background: Azadirachta indica (Neem) is a medicinal plant that is traditionally known for its antimicrobial properties. The present study was aimed to determine the bioactive components of the A. indica leaves using GC-MS. Results: Results revealed presence of 35 different active compounds in different percentage composition successions. Bioactive compounds listed include; Methenamine, Hexadecanoic acid, methyl ester; Phenol; Dodecanoic acid, methyl ester; Methyl tetradecanoate; sec-Butylamine; 2-Propanone, 1-methoxy-; 10-Octadecenoic acid, methyl ester; Heptadecanoic acid, 16-methyl-; Phenol, 2,6-dimethoxy-; Phenol, 2-methoxy-; n-Hexadecanoic acid. Their molecular weight and formula was observed while their biological activities were also illustrated. Conclusions: The findings of this study suggest that A. indica leaf collected from the study area contain sec-Butylamine and Methenamine that have not been identified from other studies which are important bioactive compounds that can be used in several biological activities.

Azadirachta indica, Neem, GC-MS, Bioactive, Sec-Butylamine, Methenamine

Ihenetu, F. , Okorondu, S. , Chikwendu, C. , Nwabueze, R. and Anekwe, I. (2024) Identification of Sec-Butylamine and Methenamine and Other Bioactive Compounds from Edible Azadirachta indica Methanolic Extracts Using GC-MS. Open Access Library Journal, 11, 1-17. doi: 10.4236/oalib.1109750.