Author(s)

Bibiana I. Oti¹, Geoffrey Okorie¹, Peter Chime¹, Ethel Chime^1,2, Birinus Ezeala-Adikaibe², Casmir Orjioke¹, Fintan Ekochin^1*, Michael C. Abonyi¹

¹Enugu State University Teaching Hospital, Enugu, Nigeria.
²University of Nigeria Teaching Hospital, Ituku-Ozalla, Nigeria.

Gordon Holmes Syndrome is a rare inherited disease characterized by both neurological and reproductive signs and symptoms. Most patients develop neurologic challenges in early adulthood and cerebellar ataxia occurs as the disease progresses. In the majority of patients, hypogonadism is hypogonadotropic but rarely hypergonadotropic. We report a case of a 26-year-old female in Nigeria, with hypergonadotropic hypogonadism and cerebellar atrophy from a non-consanguineous marriage and no family history.

Gordon Holmes Syndrome, Hypergonadotrophic Hypogonadism, Cerebellar Ataxia, Neuroendocrine Disorder

Oti, B. , Okorie, G. , Chime, P. , Chime, E. , Ezeala-Adikaibe, B. , Orjioke, C. , Ekochin, F. and Abonyi, M. (2024) Hypergonadotrophic Hypogonadism with Cerebellar Ataxia in a Twenty-Six-Year-Old Female: A Case Report. Open Journal of Modern Neurosurgery, 14, 83-90. doi: 10.4236/ojmn.2024.141009.