Author(s)

Appy Simone Abé¹, Kouao Augustin Amonkan¹, Kacou Jules Marius Djétouan^1*, Koffi Joseph N’guessan², N’dah Etchien Christelle Ekra², Kesse Philippe N’da³, Koffi Bruno Koko¹, Akoua Jeanne Kanga¹

¹UPR-Nutrition and Pharmacology, Laboratory of Biology and Health, UFR-Biosciences, Félix Houphouët-Boigny University, Abidjan, Cõte d’Ivoire.
²UPR-Animal Physiology, Phytotherapy and Pharmacology, Laboratory of Biology and Health, UFR-Biosciences, Félix Houphouët-Boigny University, Abidjan, Cõte d’Ivoire.
³Laboratory of Industrial Processes, Synthesis, Environment and New Energy (LAPISEN), Institute National Polytechnique Félix Houphouët-Boigny, Yamoussoukro, Cõte d’Ivoire.

Plant of Bambusa vulgaris is used in traditional medicine practice for the management of many pathologies including hypertension. The effect of the aqueous extract of the leaves of Bambusa vulgaris on blood pressure was evaluated in normotensive male rabbits. Blood pressure was measured by the invasive method. Thus, aqueous extract of Bambusa vulgaris leaves had been injected intravenously at doses ranging from 1 mg/kg to 30 mg/kg in rabbits anesthetized with thiopental. The effects of this extract on blood pressure were also evaluated in rabbits having previously received different doses of atropine. The aqueous extract of Bambusa vulgaris leaves induced a dose-dependent hypotension which is not canceled in the presence of atropine. The results obtained show that the extract has blood pressure lowering effect which may be mediated by muscarinic-type cholinergic receptors.

Bambusa vulgaris, Aqueous Extract, Hypotensive Effects, Oryctolagus cuniculus Rabbits, Atropine

Abé, A. , Amonkan, K. , Djétouan, K. , N’guessan, K. , Ekra, N. , N’da, K. , Koko, K. and Kanga, A. (2023) Hypotensive Effects of an Aqueous Extract of Bambusa vulgaris (Poaceae) Leaves in Rabbit Oryctolagus cuniculus. Journal of Biosciences and Medicines, 11, 51-59. doi: 10.4236/jbm.2023.118005.