Author(s)

Manju Domnick^1*, Martin Domnick¹, Iris Ernst², Frank P. Müller³, Viktor Rempel⁴, Norman Bitterlich⁵, Hüseyin Sahinbas⁶, Stefan Könemann⁷, Stathis Philippou⁸

¹Praxis and Praxisklinik Domnick, Herten, Germany.
²German Centre for Stereotaxy and Precision Radiation (DZSP), Soest, Germany.
³Catholic Karl Leisner Clinic gGmbH, Kleve, Germany.
⁴St. Anna Hospital Herne, Herne, Germany.
⁵Medizin & Service GmbH, Chemnitz, Germany.
⁶Praxis für Hyperthermie, Düsseldorf, Germany.
⁷Radiotherapy Centre Bochum, Bochum, Germany.
⁸Institute of Pathology of the Augusta Hospital, Bochun, Germany.

The aim of this report was to describe the feasibility, overall survival and quality of life of combining multimodal therapy with a complementary therapy concept called LOTUS Care Cure program. The peritoneal carcinomatosis (PC) working group described their observations on the combination of multimodal therapy with a complementary therapy concept based on 132 patients with different cancer entities with suspected PC. PC was not confirmed by laparoscopy in 32.5% of the patients included in the working group of patients with suspected PC. Patient compliance and the feasibility were high. For Ki67, there is a cut-off at 45% with a slower progression at <45% and a faster progression of the disease at >45%. The higher the Karnofsky index, the more improved the therapy and tolerability, with a cut-off of 80%. Overall, 72.0% of patients died. The median survival time in the overall population was 3.74 years (95% CI, 2.57 to 4.91) with a sharp decline in the first 16 weeks. The quality of life of patients can be improved with the implementation of the complementary LOTUS Care Cure Project. Overall, the therapy of PC requires a multi-professional team of therapists and a multimodal therapy concept. The multimodal concept together with the Lotus Care Cure project shows very good feasibility with high compliance and ultimately leads to better and low-risk patient care.

Multimodal and Complementary Therapy, Peritoneal Carcinosis, Quality of Life

Domnick, M. , Domnick, M. , Ernst, I. , Müller, F. , Rempel, V. , Bitterlich, N. , Sahinbas, H. , Könemann, S. and Philippou, S. (2022) Observations from the Working Group Peritoneal Carcinosis. Journal of Cancer Therapy, 13, 507-524. doi: 10.4236/jct.2022.138045.