Author(s)

Hiroto Shoji^*, Ryo Iwamoto

Department of Science and Technology, Kwansei Gakuin University, Sanda, Hyogo, Japan.

Columnar outer hair cells of the inner ear form V-shaped bundles, which are arranged in three rows in the cochlea. If the formation of these V-shaped bundles is disturbed, sensorineural hearing loss occurs. To quantify the distribution of V-shaped bundles, the use of a Turing-type reaction-diffusion (RD) system, including anisotropic diffusion, should be considered. We found that a periodic triangle pattern appears based on the anisotropy in the RD system. Then, using the proposed RD system, the image of the V-shaped bundle was examined. The results showed that the correlation between the RD pattern and V-shape bundles not only classifies the experimental result but also significantly differs in the number of directional changes in a set of V-shape bundle. Therefore, this process can help quantify the images of V-shaped bundles.

Reaction-Diffusion, Turing, Triangle, Inner Ear

Shoji, H. and Iwamoto, R. (2022) Reaction-Diffusion Algorithm for Quantitative Analysis of Periodic V-Shaped Bundles of Hair Cells in the Inner Ear. Journal of Biosciences and Medicines, 10, 240-251. doi: 10.4236/jbm.2022.103022.