Background: A less risky sexual behaviour for sexual and reproductive health among HIV positive women is essential for their well-being and that of their sexual partners and children. The aim of this study was to assess the frequency of dual contraception method use and factors associated among HIV positive women follow-up at the treatment center unit (TCU) at Yaounde Central Hospital (YCH). Methods: It was a transversal study done for 6 months at YCH. A sample of 294 HIV positive women among 322 who came for consultation and received their treatment during our study period was included. Data collection was by face-to-face questionnaire administration. Data were analysed using Epi-infos 7.1.3.3 software. Multiple logistic regression was done to find an association between the outcome and predictor variables with statistically significant level of p < 0.05 and CI of 95%. Results: Prevalence of DCM use was 33.3%. Multivariate logistic regression showed that DCM utilization was associated with age > 35 [(AOR = 0.29, 95% CI (0.14 - 0.60], sexual frequency (AOR = 0.25, 95% CI (0.10 - 0.60)], parity and gravidity of less than 3, (AOR = 0.29, 95% CI (0.14 - 0.58) and (AOR = 0.28, 95% CI (0.12 - 0.65)] respectively and no past history of abortion [(AOR = 0.24, 95% CI (0.10 - 0.56)]. All were protective factors. Conclusion: DCM use prevalence among HIV positive women was low. Age > 35 years, one or more than one sexual intercourse per week, parity and gravidity of less than 3 and no past history of abortion were associated with DCM use.