Author(s)

Tatiana Miranda Deliberador, Suyany Gabriely Weiss, Felipe Rychuv, Gabriele Cordeiro, Michele Caroline Lima Ten Cate, Lucas Leonardi, João Armando Brancher, Rafaela Scariot

Department of Dentistry, School of Health Sciences, Universidade Positivo, Curitiba, Brazil.

Oxygen is an essential nutrient for cellular metabolism, especially energy production. The substance is involved in multiple processes including oxidative killing of bacteria, reepithelialization, angiogenesis, and collagen synthesis. In order to test and compare the effects of the oxygen gel blue^®m in vitro on Porphyromonas gingivalis, four groups were evaluated: 100% oxygen gel (B1), 75% oxygen gel (B2), 50% oxygen gel (B3), and 100% 0.12% chlorhexidine digluconate solution (C1). For this purpose, evaluations of the proportion of bacterial growth were performed, using the Agar diffusion test. The results demonstrated that blue^®m at a dose of 100% and 75% is similar to chlorhexidine (p > 0.05); however blue^®m at a concentration of 50% showed a lower inhibition halo when compared to chlorhexidine (p = 0.024). blue^®m at higher concentrations provided inhibitory halo of Porphyromonas gingivalis similar to chlorhexidine digluconate, while blue^®m at lower concentration had a lower bacterial inhibition halo compared to chlorhexidine.

Porphyromonas gingivalis, Periodontics, Chlorhexidine, Oxygen

Deliberador, T. , Weiss, S. , Rychuv, F. , Cordeiro, G. , Cate, M. , Leonardi, L. , Brancher, J. and Scariot, R. (2020) Comparative Analysis in Vitro of the Application of blue^®m Oral Gel versus Chlorhexidine on Porphyromonas gingivalis: A Pilot Study. Advances in Microbiology, 10, 194-201. doi: 10.4236/aim.2020.104015.